NanoXome™
better for life
Ashkan's proprietary NanoXome™ combines the precision of nanotechnology with the efficiency of liposomal delivery to enhance the bioavailability, absorption and delivery of the carefully selected and scientifically sound ingredients in our products.
What is Nanotechnology?
Nanotechnology involves working with materials at an incredibly small scale – so small that it is measured in nanometers (one billionth of a meter). To put it in perspective, a nanometer is about 100,000 times smaller than the width of a human hair!
Copyright: Singh Y. et al. Journal of Controlled Release, Volume 252, 28
April 2017, Pages 28-49 comparison
How NanoXome™ Works
Oral nanoparticles have a carrier function, promote intestinal absorption, improve oral bioavailability, prevent diseases, and have therapeutic applications.
NanoXome™ nanoparticles are designed to traverse the strong digestive environment of the mouth and stomach, as they make their way to the small and large intestines, wherein they are actively absorbed.
Copyright: Singh Y. et al. Journal of Controlled Release, Volume 252, 28
April 2017, Pages 28-49 comparison
This process involves creating tiny droplets or structures called micelles and liposomes, through specialized processes, forming nano-emulsions.
Nano-emulsions show better penetration efficacy of the ingredients due to the large surface area and low surface tension of the whole emulsion system.
Benefits of NanoXome™ Technology
The benefits of NanoXome™ technology allows for:
Copyright: Mustafa I.M, et al. Nanomaterials 2020, 10, 1608
NanoXome™ vs Traditional Delivery
| Feature | NanoXome™ | Traditional |
|---|---|---|
| Absorption | Releases nutrients in the intestine | Mostly lost in digestion |
| Stability | Protects nutrients from breakdown | Unstable in stomach acid |
| Compatibility | Works with many nutrient types | Prone to ingredient interactions |
| Bioavailability | Very high | Low to moderate |
| Therapeutic Response | Faster | Slower |
| Side Effects | Gentle on digestion | Generally causes gastric irritation |
NanoXome™ – Backed by Science
A 2019 study published in the International Journal of Veterinary Science, investigating the immune-modulating effects of Aviboost®, a product created and manufactured by Ashkan using our NanoXome™ technology, demonstrated significant growth in the height of intestinal villi and improved immune response in the experiment group versus the control group of broiler chickens.
The results confirm that the application of Ashkan's NanoXome™ delivers superior absorption and therefore unmatched efficacy.
References
- Balamurugan K and Chintamani P, Lipid nano particulate drug delivery: An overview of the emerging trend, The Pharma Innovation Journal 2018; 7(7): 779-789
- Raheel IAR, Orabi A, Hala SH Salam, Abed AH, Fouad IA and M Refaa. Immune-Modulating Effects of Aviboost® Nucleotides on The Intestinal Epithelium of Broiler Chickens. International Journal of Veterinary Science. March 14, 2019
Copyright: Singh Y. et al. Journal of Controlled Release, Volume 252, 28 April 2017, Pages 28-49
Copyright: Mustafa I.M, et al. Nanomaterials 2020, 10, 1608